Radiation synovectomy is an attractive alternative to surgical or chemical synovectomy for the rheumatoid arthritis. The procedure requires only an intra-articular injection of a radiopharmaceutical with the appropriate nuclear radiation to counteract and control synovial inflammation. Lots of patients and studies have responded well or shown the effectiveness. In this article the biological and clinical results obtained with radiation synovectomy are summarized and reviewed. Radionuclide characteristics

kinds of carriers

evaluation of dosimetry and methods of controlling particle size so as to minimize the leakage from the cavity are thoroughly discussed.