Clinical application of FDG PET for the diagnosis of recurrence in glioma

ZUO Chuantao  LIU Yongchang  GUAN Yihui  ZHAO Jun  LIN Xiangtong

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Clinical application of FDG PET for the diagnosis of recurrence in glioma

更新时间：2021-03-12

- Clinical application of FDG PET for the diagnosis of recurrence in glioma
- NUCLEAR TECHNIQUES Issue 11, (2001)
- 作者机构：
  
  1. 复旦大学附属华山医院
  2. 复旦大学附属华山医院,上海,200040
- 作者简介：
- 基金信息：
- DOI：
  CLC： R739.4
- Published：01 November 2001
- 稿件说明：
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[1]左传涛,刘永昌,管一晖,赵军,林祥通.FDG-PET在胶质瘤复发诊断中的临床应用[J].核技术,2001(11):899-902.

ZUO Chuantao LIU Yongchang GUAN Yihui ZHAO Jun LIN Xiangtong. Clinical application of FDG PET for the diagnosis of recurrence in glioma[J]. Nuclear techniques, 2001, (11): 899-902.
[1]左传涛,刘永昌,管一晖,赵军,林祥通.FDG-PET在胶质瘤复发诊断中的临床应用[J].核技术,2001(11):899-902. DOI：

ZUO Chuantao LIU Yongchang GUAN Yihui ZHAO Jun LIN Xiangtong. Clinical application of FDG PET for the diagnosis of recurrence in glioma[J]. Nuclear techniques, 2001, (11): 899-902. DOI：

摘要

为评价18FDG -PET在胶质瘤复发和坏死鉴别诊断中的价值

对经手术治疗或放射治疗后的脑胶质瘤患者 15例进行PET检查。结果表明

随访证实复发的 12例胶质瘤患者中

11例的FDG -PET显像结果提示肿瘤复发

另外未复发的 3例患者

FDG -PET结果提示无复发。FDG-PET显像表明

胶质瘤复发可以表现为原发部位片状、环状、点状FDG摄取及远隔部位FDG摄取增高。肿瘤复发病变最高放射性浓度比平均白质放射性浓度的比值为 2 .85± 1.0

而未复发或放射性改变组织的最高放射性浓度比平均白质放射性浓度的比值为 1.32± 0 .0 7

两者之间差异显著（P <0 .0 5 ）。结果提示

FDG -PET显像有助于胶质瘤放射治疗后患者放射性坏死和复发的鉴别。

Abstract

To evaluate the role of 18 FDG-PET in the differential diagnosis of recurrence and radionecrosis in glioma. FDG-PET scans in 15 glioma patients were performed after initial surgery and radiation therapy. Results of the 12 tumor recurrence

11 FDG-PET scans showed hypermetabolism

3 patients with hypometabolic abnormalities on FDG-PET scan had no evidence of recurrence. In recurrence

the primary site showed platelike

ringform and tocal FDG uptake and also increased uptake in remote area. In tumor recurrent patients

the lesion’s highest radioactivity/average white matter radioactivity ratio was 2.85±1.0

while the ratio of radionecrosis was 1.32±0.07

the differences were significant. Conclusions show that FDG-PET scans are helpful in the differentiation between tumor recurrences and radionecrosis in glioma.

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