Mutagenic effects of Streptomyces ribosidificus

Streptomyces kanamyceticus and the phage-resistant culture of Streptomyces kanamyceticus induced by N+ and C+ ion implantation with different doses have been investigated.The experimental results show that the death rates of antibiotic-producers increase with the increase of ion implantation dose

and the form mutation of the antibiotic-producers is rather obvious. After N+ ion implantation

the titer units increase by 10%-25%

5.2%12.1% and 2.1%-12.75% for the above three strains respectively; while after C+ion implantation the titer units increase by 10%-16.9%

1.05%-3.08% and 5%-20% respectively.The selected strains of Micromonospora echimospoora and Streptomyces kanamyceticus after N+ ion implantation have been used in the factory.The increase of production is 20% and 12.5% respectively

showing marked economic benefits are obtained.